G-I-N 2016 Scientific Committee
Christine Laine, MD, MPH, 2016 Scientific Committee Chair
Brian Alper, MD, MSPH, FAAFP
Michael Barry, MD, MACP
Helen Burstin, MD, MPH, FACP
Vivian Coates, MBA
David Goldmann, MD, FACP
Fergus Macbeth, MA, DM, FRCP, FRCR
Joerg Meerpohl, MD
Bernadette Melnyk, PhD, RN, CPNP/PMHNP, FAAN
Mary Nix, MS, MT (ASCP), SBB
Susan Norris, MD, MPH, MS
Monika Nothacker, MD, MPH
Amir Qaseem, MD, PhD, MHA, FACP
Corinna Schaefer, MA
Holger Schünemann, MD, PhD, MSc, FRCP (C), FACP
Craig Umscheid, MD, MSCE, FACP
Dr. Christine Laine is Editor-in-Chief of Annals of Internal Medicine and Senior Vice President of the American College of Physicians. She is board-certified in internal medicine and sees patients and is on the faculty at Jefferson Medical College in Philadelphia.
Dr. Laine received her medical degree from SUNY Stony Brook, and completed residency at The New York Hospital (Cornell University) and fellowship in general internal medicine and clinical epidemiology at Beth Israel Hospital (Harvard University). Dr. Laine’s master of public health degree is from Harvard University.
She holds leadership positions in the International Committee of Medical Journal Editors, the Council of Science Editors, and the World Association of Medical Editors.
Jos Kleijnen, MD, 2016 Scientific Committee Vice Chair
Dr. Jos Kleijnen did both his medical study and his PhD in Maastricht, where he worked for 6 years in the department of Epidemiology pioneering the methods of doing systematic reviews, in those days on topics of food supplements and alternative medicine. He then moved in 1993 to the Academic Medical Center in Amsterdam to work as a clinical epidemiologist with clinicians and health professionals on their various research projects.
In 1994, Jos founded the Dutch Cochrane Centre and became its first director. In 1998 he was tempted to take on the position of professor and director at the Centre for Reviews and Dissemination at the University of York in the UK. He remained in that job until 2005, when he left to start his own company Kleijnen Systematic Reviews Ltd, also based in York, UK. In 2011, while still remaining in York as the main base, he was appointed in a part-time position as professor of systematic reviews in health care at CAPHRI. Jos has been a keen contributor to the Cochrane Collaboration since its inception in 1993, and is also a strong supporter of the Joanna Briggs Institute in Adelaide, Australia, where he holds a position as clinical professor. Finally, Jos also served on the G-I-N Board from 2003-2005.
Dr. Brian S. Alper is the founder of DynaMed and the Vice President of Evidence-Based Medicine Research and Development, Quality and Standards for EBSCO Health, at EBSCO Publishing, Inc. As a medical student Alper realised he could not possibly memorise sufficient medical information to support practice so he began organising what he was learning electronically. Dr. Alper discovered that his organised information was more useful than textbooks or existing resources used during clinical rotations. During a rotation in rural practice in Eastern Tennessee, Alper saw his disease summary notes making real differences in diagnosis and treatment every day. At this point, the notes weren't in a sophisticated system but he realised that health care professionals needed this kind of resource and has been working to serve this need ever since. As a result, Alper created DynaMed (Dynamic Medical Information System), a clinical reference tool to provide the most useful information to health care professionals at the point of care, and he created a systematic way to monitor current literature and continuously update DynaMed based on the best available evidence.
Dr. Alper earned his MD at Hahnemann University, completed residency in family medicine at Penn State University/Good Samaritan Hospital, and a fellowship at the University of Missouri-Columbia. He is a clinical research assistant professor at University of Missouri-Columbia. He has conducted original research and systematic reviews and taught evidence-based medicine to medical students, residents, fellows and faculty. He has presented numerous lectures and workshops at educational programs, hospitals and national and regional professional meetings and has served as the Co-Chair of the Society of Teachers of Family Medicine Group on Evidence-Based Medicine.
In mid-2005, DynaMed became a member of the EBSCO Publishing family. Dr. Alper saw this union as the best way to continue the DynaMed mission of providing the most useful information to health care professionals at the point of care. As part of EBSCO Publishing, DynaMed continues to grow, improve and provide the best available evidence updated daily for the DynaMed Community which now reaches thousands of hospitals and hundreds of thousands of clinicians in more than 125 countries.
Dr. Alper is a Fellow of the American Academy of Family Physicians (AAFP), and is a member of the American College of Physicians (ACP), Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group, Guidelines International Network (G-I-N), Health Level 7 (HL7) Clinical Decision Support Work Group, the Rosalind Franklin University Global Health Advisory Board, and World Association of Medical Editors (WAME).
Dr. Michael Barry became president of the nonprofit Informed Medical Decisions Foundation in 2009. In 2014, the Foundation became a division of Healthwise, another mission-driven nonprofit. Michael remains president of the Foundation and adds the title of Chief Science Officer at Healthwise. Healthwise’s mission is to help people make better health decisions.
He is a past president of the Society for Medical Decision Making (SMDM) and the Society of General Internal Medicine in the United States. Michael has led many prominent research studies including the Patient Outcome Research Team for Prostatic Diseases. Michael continues to practice primary care and serves as medical director of the John D. Stoeckle Center for Primary Care Innovation at MGH. He is also a professor of medicine, part time, at Harvard Medical School and a Master of the American College of Physicians.
Helen Burstin, MD, MPH, FACP is the Chief Scientific Officer of The National Quality Forum, a not-for-profit membership organization that works to catalyze healthcare improvement through quality measurement and reporting. Dr. Burstin is responsible for advancing the science of quality measurement and improvement. She provides scientific oversight for the evaluation, endorsement and selection of quality measures and the transition to electronic performance measurement.
Prior to joining NQF in 2007, Dr. Burstin was the Director of the Center for Primary Care, Prevention, and Clinical Partnerships at the Agency for Healthcare Research and Quality (AHRQ). In her role, she oversaw the development of an extensive research portfolio at the intersection of health information technology and quality of care. Her center also supported the U.S. Preventive Services Task Force and research on primary care and prevention. She led the development of the first National Healthcare Disparities Report. Prior to joining AHRQ in 2000, Dr. Burstin was an Assistant Professor at Harvard Medical School and the Director of Quality Measurement at Brigham and Women’s Hospital. In her role, she developed a hospital-wide electronic Quality Measurement Reporting System. She also served as the Chair of the Medical Staff Executive Committee on Quality Assurance and Risk Management.
Dr. Burstin is a graduate of the State University of New York at Upstate College of Medicine and the Harvard School of Public Health. Dr. Burstin completed a residency in primary care internal medicine at Boston City Hospital. After residency, she completed fellowship training in General Internal Medicine and Health Services Research at Brigham and Women's Hospital and Harvard Medical School. Dr. Burstin is the author of more than 80 articles and book chapters on quality, patient safety, and disparities. She served as chair of the Quality Measures Workgroup of the federal HHS Health IT Policy Committee. She is a Senior Professorial Lecturer in the Department of Health Policy at George Washington University School of Public Health. Dr. Burstin is a Clinical Associate Professor of Medicine at George Washington University where she serves as a preceptor in internal medicine. She was recently awarded the Alpha Omega Alpha Medical Voluntary Attending Award from the George Washington School of Medicine.
Ms. Vivian Coates developed and leads ECRI Institute’s evidence-based medicine & health technology assessment program, including the Evidence-based Practice Center (EPC) and the Health Technology Assessment Information Service (HTAIS) for health plans, hospitals/health systems, and health policymakers. She initiates and fosters relationships with users of comparative effectiveness and health technology assessment information to promote evidence-based approaches for healthcare coverage, purchasing, delivery, and clinical practice guideline development.
Ms. Coates serves as project director on ECRI’s contract to create, maintain and enhance the National Guideline Clearinghouse and the National Quality Measures Clearinghouse, sponsored by the Agency for Healthcare Research and Quality (AHRQ). The clearinghouses are public resources for information on specific evidence-based clinical practice guidelines and quality measures.Ms. Coates is also responsible for the ECRI contract to create the nation’s first Healthcare Horizon Scanning System for AHRQ, monitoring thousands of new drugs, devices, biologics and procedures across 14 different priority areas. The AHRQ Healthcare Horizon Scanning System focuses on emerging health care technologies and innovations to better inform patient-centered outcomes research investments at AHRQ through the Effective Health Care Program.
As a member of ECRI’s Executive Staff, Ms. Coates also has broad management responsibilities that include the recruitment and oversight of personnel resources as well as the acquisition of material resources to support ECRI's mission to improve the safety, efficacy and cost effectiveness of healthcare.
Dr. David R. Goldmann is Vice President and Chief Medical Quality Assurance Officer in the Clinical Solutions division at Elsevier. As director of the Elsevier’s Evidence-Based Medicine Center, he leads an initiative to generate rapid systematic reviews for integration into the company’s print and electronic content. In addition, he and his colleagues in the Centre provide education and training in evidence-based medicine, offer consultation to Elsevier content developers and manage a quality assurance program.
Dr. Goldmann formerly served as Editor-in-Chief of First Consult, an electronic point-of-care clinical tool and part of Clinical Key, Elsevier’s extensive medical knowledge resource designed to provide physicians with rapid access to evidence-based answers to clinical questions.
Dr. Goldmann is an Emeritus Associate Professor of Medicine in the Perelman School of Medicine at the University of Pennsylvania and a member of the Division of General Internal Medicine in the Department of Medicine. Having practiced internal medicine at Penn for many years and participated in various clinical and teaching activities, he is a now a member of Penn’s Center for Evidence-Based Practice, which develops systematic reviews and guidelines used by various stakeholders within the University of Pennsylvania Health System.
Dr. Goldmann has an extensive background in medical editing and publishing. At the American College of Physicians, he served as Editor-in-Chief of the Physicians’ Information and Education Resource (PIER), another electronic, evidence-based, point-of-care medical decision support tool.
He has held various editorial positions at Annals of Internal Medicine where he initiated the Medical Writings section of the journal and developed a format for structured book reviews. He also served as editorial consultant to the book program at the ACP and has edited several patient education books.
Dr. Goldmann came to Philadelphia for his residency in internal medicine at the University of Pennsylvania in 1972. After residency and a fellowship in endocrinology and metabolic disease at Penn, he joined the Department of Medicine. He directed the medical consultation service and edited one of the first textbooks in consultative medicine.
He received a Bachelor of Arts degree from Harvard University, a medical degree from Harvard Medical School and a Master of Arts degree from the University of Sussex in England. He is a Fellow of the American College of Physicians.
Dr. Fergus Macbeth recently retired from active clinical work after working as a consultant oncologist in Glasgow and Cardiff. He has also worked for the National Institute for Health and Care Excellence (NICE) for almost 10 years, first as Director of the National Collaborating Centre for Cancer, developing cancer guidelines for NICE and latterly, until his retirement, as Director for the Centre for Clinical Practice, responsible for NICE’s wider clinical guidelines and quality standards programmes. He still works part time as Mentor to NICE Fellows and Scholars and is currently chairing the NICE guideline on melanoma.
He has a long standing clinical and research interest in lung cancer, leading and participating in important clinical trials. He has been Coordinating Editor of the Cochrane Lung Cancer Review Group for 5 years and is currently Associate Director of the Wales Cancer Trials Unit, Cardiff and Honorary Professor at Cardiff University. He teaches for the UK Cochrane Centre and the Collaboration for Evidence Based Healthcare in Africa.
Dr. Okwen Patrick Mbah is a Cameroonian medical doctor and health economist with an interest in improving global health outcomes and does public health research, systematic reviews with both Cochrane and Campbell Collaborations.
He currently works at the North West Regional Fund for Health Promotion. Affiliated to the Catholic University of Cameroon (CATUC) department of Health Economics and the Centre for the Development of Best Practices in Health (CDBPS-H), Patrick also works as a health consultant to several international development agencies and governments. Within G-I-N Patrick is the lead of the African G-I-N community.
Dr. Joerg Meerpohl is a board-qualified pediatrician and pediatric hematologist and oncologist. He has been working as a researcher at the German Cochrane Centre since 2007 and was appointed deputy director in 2011 and co-director in 2015. His main research interests include systematic review methodology, transparency in research and related dissemination bias as well as reporting quality. Since 2015, Joerg is a member of the Cochrane Steering Group.
For many years Joerg has been an active member of the GRADE working group, and has run many GRADE workshops at national and international organisations. Joerg worked as GRADE methodology advisor with several WHO panels, the European Stroke Organisation and the Robert Koch Institute in Germany amongst others. In 2013 he founded the GRADE centre in Freiburg, Germany and is a member of the GRADE guidance committee.
Dr. Bernadette Mazurek Melnyk is recognised nationally and globally for both her research-based and innovative approaches to a wide range of health care challenges. She serves as Associate Vice President for Health Promotion, University Chief Wellness Officer, and Professor and Dean of the College of Nursing at The Ohio State University. Also a professor of pediatrics and psychiatry at Ohio State’s College of Medicine, Dr. Melnyk’s expertise spans evidence-based practice, intervention research, child and adolescent mental health, and health and wellness. In addition, she is editor of the journal Worldviews on Evidence-based Nursing, which under her leadership has risen in impact factor ranking to #3 of more than 100 nursing journals.
In 2013, she became one of the few nurses elected to the Institute of Medicine – now the National Academy of Medicine whose members counsel government and private sector leaders to help them make informed health decisions. Dr. Melnyk served a four year term on the 16-member United States Preventive Services Task Force, an independent group of national experts working to improve the health of all Americans by making evidence-based recommendations about clinical preventive services. She also founded and serves as first president for the National Consortium for Building Healthy Academic Communities, a collaboration of universities across the U.S. dedicated to the improvement of population health and well-being in institutions of higher learning.
Dr. Melnyk has received numerous national and international awards, including: the Jessie Scott Award from the American Nurses Association, recognising her work to improve health care quality through the integration of research, education and practice; the NIH/National Institute of Nursing Research’s inaugural Director’s Lectureship award, the National Organisation of Nurse Practitioners’ Lifetime Achievement Award, and induction into Sigma Theta Tau International’s Research Hall of Fame.
Dr. Melnyk earned her Bachelor of Science in Nursing degree from West Virginia University, her Master of Science degree with a specialisation in nursing care of children and pediatric nurse practitioner from the University of Pittsburgh, and her PhD in clinical research from the University of Rochester – where she also completed her post-master’s certificate as a psychiatric mental health nurse practitioner. She is also an elected fellow of the American Academy of Nursing, the National Academies of Practice, and the American Association of Nurse Practitioners. Her record of scholarship includes over 19 million dollars of sponsored funding from federal agencies as PI and 285 publications, including four books.
Ms. Mary Nix has more than 30 years of experience in clinical and research settings. Clinically, she managed blood banking/transfusion medicine laboratories. She transitioned to health services research, applying the analytic skills used for success in clinical pathology to systematic evidence review and evidence-based clinical practice guideline abstraction.
Ms. Nix has certifications in biomedical informatics and project management. She has combined all of this to lead multi-million dollar, national projects for AHRQ’s Center for Evidence and Practice Improvement; these are projects that use data meeting explicit criteria, informatics, technology and design to disseminate evidence-based clinical practice guidelines, health care quality measures, and service and policy innovations, and affect their implementation by practitioners, providers, purchasers, and policy makers.
Dr. Susan Norris has extensive experience with systematic reviews and guideline development related to clinical medicine and public health. For the last three years, she is Secretary of the World Health Organisation (WHO) Guideline Review Committee, where she is responsible for quality assurance of all proposals and final guidelines produced by WHO, for training in guideline development for WHO staff at headquarters and in the regional offices, and for quality improvement of WHO guidelines internationally. She wrote the second edition of the WHO handbook for guideline development (2014) and has led numerous initiatives within WHO to improve guideline quality, including the development of guidance on how to develop evidence-informed, rapid advice guidelines in the context of a public health emergency or humanitarian crisis.
Dr. Norris received her MD and MSc in Experimental Surgery from the University of Alberta, Canada, and MPH from the University of Washington, Seattle, WA, USA. She practiced primary care medicine for 10 years, and was involved in the development of evidence-based care processes at the health care system and practice levels. She has also worked at the US Centers for Disease Control and Prevention, where she led a systematic review team which supported public health guidelines related to diabetes. Dr. Norris is an Associate Professor in the Departments of Family Medicine at Oregon Health and Science University, in Portland, Oregon, USA, where she led research teams conducting systematic reviews for numerous governmental and physician specialty organisations. Her research interests include conflict of interest in guideline development, selective outcome reporting bias, and the use of nonrandomised studies in systematic reviews.
-1994-2000 Trained as a medical specialist for gynecology and obstetrics, PhD 1999,
- 2001-2005 outpatient gynecologist and senior physician at a department of gynecology and
obstetrics in Berlin
- 2001-2003 postgraduate Public Health studies (master of Public Health 2005)
- 2005-2006 project manager and head of section “benchmarking and quality assurance” at the West-German breast center, Düsseldorf
- 2006-2010 scientific associate section “Evidence based medicine and guidelines”, agency for quality in medicine (AZQ)
- 2010-2012 head of section knowledge management/internal quality management (AZQ)
- Since 2012 scientific associate and deputy head AWMF-institute of medical knowledge management
- Lecturer at the Berlin school of public health, Charité
- Speaker of the guidelines section, German Network for Evidence based Medicine
- Chair of the G-I-N Performance Measures Working Group: special interest in guidelines based performance measures and individualisation of guideline recommendations
Dr. Amir Qaseem is responsible for leading the American College of Physicians' evidence-based medicine and clinical practice guidelines program, one of the oldest programs in the United States, including writing of the clinical guidelines, and overseeing the College’s Clinical Guidelines Committee. Dr. Qaseem is also in charge of directing the ACP's physician performance measurement program and is responsible for ACP’s Performance Measurement Committee. He also leads the High Value Care Task Force evaluating and publishing the benefits, harms, and costs of various overused, misused, and underused diagnostic tests and therapeutic interventions. Dr Qaseem’s work includes development and implementation of ACP’s quality improvement and educational programs.
Dr. Qaseem is also involved in several international collaborations to develop joint clinical guidelines and improve quality of care across different countries. Dr. Qaseem has published numerous papers in peer-reviewed journals including clinical practice guidelines, implementation of clinical guidelines, quality improvement, performance measurement, and health policy related issues. Some of the papers authored by Dr. Qaseem are in the top ten most read articles in the Annals of Internal Medicine. Dr. Qaseem has been invited to speak and has presented at several national and international conferences on issues related to health policy, evidence-based medicine, guideline development, guideline and evidence grading, and topics associated with performance measurement and quality of care. Dr Qaseem is also on governance boards and committees of various national and international organisations. Dr. Qaseem was President of the Guidelines International Network (G-I-N) from 2012-13 and was re-elected for 2013-14. He is also a member of G-I-N Board of Trustees.
Ms. Corinna Schaefer trained and graduated in human sciences. She is head of the departments for evidence based medicine/guidelines and patient information/patient involvement at the German Agency for Quality in Medicine (ÄZQ), which she joined in 2006.
Corinna is responsible for the coordination of the German National Disease Management Guidelines Program. She co-chairs the Guidelines International Network Patient and Public Involvement Working Group (G-I-N PUBLIC).
Dr. Schünemann is chair of the Department of Clinical Epidemiology and Biostatistics at McMaster University, widely considered the birthplace of evidence-based medicine. He trained in internal medicine, epidemiology, preventive medicine and public health.
Having contributed to over 400 peer-reviewed publications (across a broad area of health care questions) he is co-chair of the GRADE working group, co-director of the World Health Organisation (WHO) collaborating center for evidence informed policy-making, a member of the Board of Trustees of the Guideline International Network, the Cochrane Collaboration Steering Group, and several other committees. He led or participated in numerous high profile guideline panels, including at the WHO, the American College of Physicians, American Thoracic Society, the World Allergy Organisation and he was a key contributor to the revised methods for WHO guideline development in 2006.
For the past 15 years, he has been advisor to ministries of health and other governmental organisations for their guideline programs. Recently, he has focused on practical application of his work by researchers and clinicians through contributions to the guideline development tool (www.gradepro.org), the guideline checklist (cebgrade.mcmaster.ca/guidecheck.html) and GRADE evidence to decision frameworks (www.decide-collaboration.eu). Maintaining an active clinical practice fulfills his passion for patient care and ensures his research is people-oriented. In his personal life, he has planned to ride the course of a Tour de France, trains vigorously and succeeded partially.
Dr. Britta Tendal is a senior advisor at the division for Hospital Services & Emergency Management at the Danish Health Authority. She has a background in systematic review methodology research and holds a Master of Science in Public Health and a PhD in Health Sciences from the University of Copenhagen.
Britta is the lead methodologist on the Danish National Clinical Guideline Program and has been involved in the development of more than 30 guidelines. She is a steering group member of Guidelines International Network Nordic (G-I-N Nordic), a member of GRADE working group and a member of Cochrane Methods Bias group.
Craig A. Umscheid, MD, MSCE is an Associate Professor of Medicine and Epidemiology at the University of Pennsylvania Perelman School of Medicine, Vice Chair for Quality and Safety in the Department of Medicine, a practicing hospitalist, and Director of the Penn Medicine Center for Evidence-based Practice (CEP), an evidence-based practice center funded by Penn to support patient care quality, safety, and value through evidence-based practice. He is also Medical Director of Clinical Decision Support at Penn, and a Senior Fellow in the Institute for Biomedical Informatics and the Leonard Davis Institute of Health Economics. Dr. Umscheid directs the medical student Evidence-based Medicine education, the Critical Appraisal certificate course, and the graduate student Systematic Reviews course. Outside of Penn, he collaborates with organisations including the Centers for Disease Control and Prevention (CDC) to assist with guideline development, and serves as the Senior Associate Director of the ECRI Institute - Penn Medicine Agency for Healthcare Research and Quality (AHRQ) Evidence-based Practice Center (EPC). He is an invited member of the PCORI Advisory Panel on Improving Healthcare Systems and the AHRQ EPC Methods Steering Committee, a past-member of the Medicare Evidence Development and Coverage Advisory Committee (MEDCAC), a former Deputy Editor of the Journal of General Internal Medicine, and former Chair of the Society of General Internal Medicine's Evidence-based Medicine Task Force. Dr. Umscheid received his undergraduate degree from Cornell, his medical degree from Georgetown, and a Masters of Science in Clinical Epidemiology from Penn. His post graduate training includes a Residency in Internal Medicine at the University of Chicago.
Dr. Jutta von Dincklage is the Head of Cancer Council Australia’s Clinical Guidelines Network. She has been leading the transition from printed to wiki-based guidelines at Cancer Council Australia over the past five years, including improving uptake and impact on clinical practice of the guidelines by piloting the implementation of online education modules. She has presented and been involved in several publications on the topic and is piloting and collaborating on strategies for living guidelines.
Jutta is a Steering Group member of the G-I-N ANZ Regional Community Group and a member of the GIN 2016 Scientific Program Committee. Prior to joining Cancer Council Australia, Jutta was involved in medical education and coordinated the piloting of the WHO Patient Safety Curriculum Guide for Medical Schools in Sydney.