Assessing risk factors as potential screening tests: a simple assessment tool.
- Assessing risk factors as potential screening tests: a simple assessment tool.
- Wald NJ, Morris JK
- Arch. Intern. Med.
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Many risk factors for disease are suggested as screening testswhen there is little prospect that they could be useful in predictingdisease. To avoid this, it is useful to know the relationshipbetween the relative risk of a disease or disorder in peoplewith high and low values of a risk factor, and the equivalentscreening performance in terms of the detection rate (sensitivity)for a specified false-positive rate. We describe an interactiveRisk-Screening Converter, accessible from the Internet (http://www.wolfson.qmul.ac.uk/rsc/),that transforms an odds ratio into the equivalent estimatesof detection and false-positive rates. The converter is intendedfor general clinicians, for people engaged in research intorisk factors and disease, and for those who give advice on applyingsuch research findings into medical practice. It should helpto distinguish effective screening methods from ineffectiveones, and so improve clinical guidelines relating to screeningand the prediction and prevention of disease.
Assessing risk factors as potential screening tests: a simple assessment tool. Wald NJ, Morris JK. Arch. Intern. Med. 2011; 171(4):286-91.