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Evidence-Based Clinical Recommendations Regarding Screening for Oral Squamous Cell Carcinomas

Overview
Title:
Evidence-Based Clinical Recommendations Regarding Screening for Oral Squamous Cell Carcinomas
Authors:
Rethman MP, Carpenter W, Cohen EE, Epstein J, Evans CA, Flaitz CM, Graham FJ, Hujoel PP, Kalmar JR, Koch WM, Lambert PM, Lingen MW, Oettmeier BW Jr, Patton LL, Perkins D, Reid BC, Sciubba JJ, Tomar SL, Wyatt AD Jr, Aravamudhan K, Frantsve-Hawley J, Cleveland JL, Meyer DM, American Dental Association Council on Scientific Affairs Expert Panel on Screening for Oral Squamous Cell Carcinomas
Journal:
J am Dent Assoc.
Publication date:
2010
Volume:
141
Issue:
5
First page:
509
Last page:
520
Publication type:
Journal
Abstract
Background. This article presents evidence-based clinical recommendations developed by a panel convened by the American Dental Association Council on Scientific Affairs. This report addresses the potential benefits and potential risks of screening for oral squamous cell carcinomas and the use of adjunctive screening aids to visualize and detect potentially malignant and malignant oral lesions. Types of Studies Reviewed. The panel members conducted a systematic search of MEDLINE, identifying 332 systematic reviews and 1,499 recent clinical studies. They selected five systematic reviews and four clinical studies to use as a basis for developing recommendations. Results. The panel concluded that screening by means of visual and tactile examination to detect potentially malignant and malignant lesions may result in detection of oral cancers at early stages of development, but that there is insufficient evidence to determine if screening alters disease-specific mortality in symptomatic people seeking dental care. Clinical Implications. The panel suggested that clinicians remain alert for signs of potentially malignant lesions or early-stage cancers while performing routine visual and tactile examinations in all patients, but particularly in those who use tobacco or who consume alcohol heavily. Additional research regarding oral cancer screening and the use of adjuncts is needed.
Preview

Evidence-Based Clinical Recommendations Regarding Screening for Oral Squamous Cell Carcinomas Rethman MP, Carpenter W, Cohen EE, Epstein J, Evans CA, Flaitz CM et al. J am Dent Assoc. 2010; 141(5):509-520.

Page last updated: Oct 14, 2010
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